Introduction: The impact of congenital anomalies on newborn mortality is determined by a number of factors, including the prevalence of congenital anomalies, the prevalence of other opposing causes of death, the superiority and accessibility of medical and surgical care, and the presence and efficacy of primary prevention policies. The aim of the study was to assess the prevalence and evaluate the clinical presentation of congenital anomalies in neonates. Material & Methods: This prospective observational study was conducted at the Pediatric Medicine and Pediatric Surgery department of Dhaka Shishu Hospital, Dhaka, Bangladesh during the period from April 2012 to September 2012. Eighty (80) newborns were included in the study using the purposive sampling method. A pre-designed questionnaire was completed for every neonate including H/O regular maternal antenatal care with the taking of TT and MMR vaccine, any maternal disease or fever with rash, taking any offending drug, use of abortifacient, exposure to radiation or industrial hazards, feeding habit including smoking or use of alcohol and clinical and anthropological examination. After collecting, the data were processed and analyzed using computer-aided statistical software SPSS (Statistical Package for Social Sciences) version 16.0 for Windows (SPSS Inc., Chicago, Illinois, USA). Ethical clearance was taken from the Ethical Review Committee (ERC) of BICH, Dhaka Shishu Hospital, Dhaka, Bangladesh. Results: Prevalence of congenital anomalies were found at 7.2%. The mean age was 4.04±3.43 days with a range from 1 to 16 days. Male infants were 52 (65.0%) and female infants were 28 (35.0%). The newborn mean weight was 2437.5±324.4 gm, and the mean length was 51.89±2.71 cm. Mean OFC was 35.19±1.21 cm (normal OFC just after birth 35 cm and normal increment in 1st month 2 cm). The mean gestational age was 35.59±2.33 weeks. The distribution of the studied patients according to their immediate outcome shows, that almost two-thirds (66.3%) of patients had been discharged with advice, DORB was 11 (13.7%) and expired 16 (20.0%). Conclusion: The hospital prevalence of birth defects is 7.2% in newborns. Birth defects are more frequent in mothers with diabetes mellitus, hypertension, consanguineous marriage, and those with irregular antenatal care.
| Published in | American Journal of Pediatrics (Volume 9, Issue 3) |
| DOI | 10.11648/j.ajp.20230903.18 |
| Page(s) | 150-153 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Congenital Anomalies, Newborn, Clinical Presentation, Prevalence
| [1] | March of Dimes Resource Center. Birth Defects. 1998. Available from: www.modimes.org. |
| [2] | Nussbaum R, Mcinnes RR, Willard HF. Thompson & Thompson: Genética Médica. Rio de Janeiro: Guanabara Koogan. 2007. |
| [3] | Nelson K, Holmes LB. Malformations due to presumed spontaneous mutations in newborn infants. N Eng J Med. 1989; 320 (1): 19-23. |
| [4] | Gillani S, Kazmi NHS, Najeeb S, Hussain S, Raza A. Frequencies of congenital anomalies among newborns admitted in nursery of Ayub Teaching Hospital Abbottabad, Pakistan. J Ayub Med Coll Abbottabad. 2011; 23 (1): 117-21. |
| [5] | Fatema K, Begum F, Akter N, Zaman SMM. Major congenital malformations among the newborns in BSMMU Hospital. Bangladesh Medical Journal 2011; 40 (1): 7-12. |
| [6] | Singh A, Gupta RK. Pattern of congenital anomalies in newborn: a hospital based prospective study. JK science. 2009; 11: 34-6. |
| [7] | Tootoonchi P. Easily identifiable congental anomalies: prevalence and risk factors. Acta Medica Iranica. 2003; 41 (1): 15-9. |
| [8] | Tayebi N, Yazdani K, Naghshin N. The prevalence of congenital malformations and its correlation with consanguineous marriages. Oman Med J. 2010; 25 (1): 37-40. |
| [9] | Samina S, Nadeem C, Sobia Q. Pattern of congenital malformations and their neonatal outcome. Journal of Surgery Pakistan (International). 2010; 15 (1): 34-7. |
| [10] | Fida NM, Al-Aama J, Nichols W, Alqahtani M. A prospective study of congenital malformations among live born neonates at University Hospital in Western Saudi Arabia. Saudi Med J. 2007; 28: 1367-73. |
| [11] | Ochieng J, Kiryowa H, Munabi I, Ibingira CBR. Prevalence, Nature and Characteristics of External Congenital anomalies at Mulago Hospital. East Cent Afr J Surg.(Online) 2011; 16 (1): 1-6. |
| [12] | Patel PK. Profile of major congenital anomalies in the Dhahira region, Oman. Ann Saudi Med. 2007; 27 (2): 106-11. |
| [13] | Swain S, Agrawal A, Bhatia BD. Congenital malformations at birth. Indian Pediatr. 1994; 31 (10): 1187-91. |
APA Style
Mizanur Rahman, Mohammad Abdullah Al Mamun, Monir Hossain. (2023). Prevalence and Clinical Presentation of Congenital Anomalies in Neonates. American Journal of Pediatrics, 9(3), 150-153. https://doi.org/10.11648/j.ajp.20230903.18
ACS Style
Mizanur Rahman; Mohammad Abdullah Al Mamun; Monir Hossain. Prevalence and Clinical Presentation of Congenital Anomalies in Neonates. Am. J. Pediatr. 2023, 9(3), 150-153. doi: 10.11648/j.ajp.20230903.18
AMA Style
Mizanur Rahman, Mohammad Abdullah Al Mamun, Monir Hossain. Prevalence and Clinical Presentation of Congenital Anomalies in Neonates. Am J Pediatr. 2023;9(3):150-153. doi: 10.11648/j.ajp.20230903.18
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ajp.20230903.18,
author = {Mizanur Rahman and Mohammad Abdullah Al Mamun and Monir Hossain},
title = {Prevalence and Clinical Presentation of Congenital Anomalies in Neonates},
journal = {American Journal of Pediatrics},
volume = {9},
number = {3},
pages = {150-153},
doi = {10.11648/j.ajp.20230903.18},
url = {https://doi.org/10.11648/j.ajp.20230903.18},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajp.20230903.18},
abstract = {Introduction: The impact of congenital anomalies on newborn mortality is determined by a number of factors, including the prevalence of congenital anomalies, the prevalence of other opposing causes of death, the superiority and accessibility of medical and surgical care, and the presence and efficacy of primary prevention policies. The aim of the study was to assess the prevalence and evaluate the clinical presentation of congenital anomalies in neonates. Material & Methods: This prospective observational study was conducted at the Pediatric Medicine and Pediatric Surgery department of Dhaka Shishu Hospital, Dhaka, Bangladesh during the period from April 2012 to September 2012. Eighty (80) newborns were included in the study using the purposive sampling method. A pre-designed questionnaire was completed for every neonate including H/O regular maternal antenatal care with the taking of TT and MMR vaccine, any maternal disease or fever with rash, taking any offending drug, use of abortifacient, exposure to radiation or industrial hazards, feeding habit including smoking or use of alcohol and clinical and anthropological examination. After collecting, the data were processed and analyzed using computer-aided statistical software SPSS (Statistical Package for Social Sciences) version 16.0 for Windows (SPSS Inc., Chicago, Illinois, USA). Ethical clearance was taken from the Ethical Review Committee (ERC) of BICH, Dhaka Shishu Hospital, Dhaka, Bangladesh. Results: Prevalence of congenital anomalies were found at 7.2%. The mean age was 4.04±3.43 days with a range from 1 to 16 days. Male infants were 52 (65.0%) and female infants were 28 (35.0%). The newborn mean weight was 2437.5±324.4 gm, and the mean length was 51.89±2.71 cm. Mean OFC was 35.19±1.21 cm (normal OFC just after birth 35 cm and normal increment in 1st month 2 cm). The mean gestational age was 35.59±2.33 weeks. The distribution of the studied patients according to their immediate outcome shows, that almost two-thirds (66.3%) of patients had been discharged with advice, DORB was 11 (13.7%) and expired 16 (20.0%). Conclusion: The hospital prevalence of birth defects is 7.2% in newborns. Birth defects are more frequent in mothers with diabetes mellitus, hypertension, consanguineous marriage, and those with irregular antenatal care.},
year = {2023}
}
TY - JOUR T1 - Prevalence and Clinical Presentation of Congenital Anomalies in Neonates AU - Mizanur Rahman AU - Mohammad Abdullah Al Mamun AU - Monir Hossain Y1 - 2023/08/17 PY - 2023 N1 - https://doi.org/10.11648/j.ajp.20230903.18 DO - 10.11648/j.ajp.20230903.18 T2 - American Journal of Pediatrics JF - American Journal of Pediatrics JO - American Journal of Pediatrics SP - 150 EP - 153 PB - Science Publishing Group SN - 2472-0909 UR - https://doi.org/10.11648/j.ajp.20230903.18 AB - Introduction: The impact of congenital anomalies on newborn mortality is determined by a number of factors, including the prevalence of congenital anomalies, the prevalence of other opposing causes of death, the superiority and accessibility of medical and surgical care, and the presence and efficacy of primary prevention policies. The aim of the study was to assess the prevalence and evaluate the clinical presentation of congenital anomalies in neonates. Material & Methods: This prospective observational study was conducted at the Pediatric Medicine and Pediatric Surgery department of Dhaka Shishu Hospital, Dhaka, Bangladesh during the period from April 2012 to September 2012. Eighty (80) newborns were included in the study using the purposive sampling method. A pre-designed questionnaire was completed for every neonate including H/O regular maternal antenatal care with the taking of TT and MMR vaccine, any maternal disease or fever with rash, taking any offending drug, use of abortifacient, exposure to radiation or industrial hazards, feeding habit including smoking or use of alcohol and clinical and anthropological examination. After collecting, the data were processed and analyzed using computer-aided statistical software SPSS (Statistical Package for Social Sciences) version 16.0 for Windows (SPSS Inc., Chicago, Illinois, USA). Ethical clearance was taken from the Ethical Review Committee (ERC) of BICH, Dhaka Shishu Hospital, Dhaka, Bangladesh. Results: Prevalence of congenital anomalies were found at 7.2%. The mean age was 4.04±3.43 days with a range from 1 to 16 days. Male infants were 52 (65.0%) and female infants were 28 (35.0%). The newborn mean weight was 2437.5±324.4 gm, and the mean length was 51.89±2.71 cm. Mean OFC was 35.19±1.21 cm (normal OFC just after birth 35 cm and normal increment in 1st month 2 cm). The mean gestational age was 35.59±2.33 weeks. The distribution of the studied patients according to their immediate outcome shows, that almost two-thirds (66.3%) of patients had been discharged with advice, DORB was 11 (13.7%) and expired 16 (20.0%). Conclusion: The hospital prevalence of birth defects is 7.2% in newborns. Birth defects are more frequent in mothers with diabetes mellitus, hypertension, consanguineous marriage, and those with irregular antenatal care. VL - 9 IS - 3 ER -
Email: